Characterisation of colonic dysplasia-like epithelial atypia in murine colitis

doi:10.3748/wjg.v22.i37.8334

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 7, 2016; 22(37): 8334-8348
Published online Oct 7, 2016. doi: 10.3748/wjg.v22.i37.8334

Table 2 Spearman’s correlation between mRNA transcript abundance and dysplasia severity

Gene	Restimate	P value
Cav1	-0.19	0.34
Ccl5	0.46	0.017^a
Cdkn2a	0.11	0.61
Cxcl5	0.29	0.15^a
Cxcl12	0.022	0.92
Il6	0.27	0.20
Muc1	-0.13	0.52
Myc	-0.26	0.20
Pparg	0.18	0.39
Prom1	0.18	0.39
Ptgs2	0.18	0.42
Spp1	0.40	0.049
Trp53	0.15	0.47
Vim	-0.14	0.51

Relationship between relative mRNA abundance (ΔΔCT) and severity of dysplasia in the distal colon was tested using Spearman’s rank correlation. Estimate of Spearman’s co-efficient of correlation (ρ) and corresponding P value for each gene are given,

^aP < 0.05.

Citation: Randall-Demllo S, Fernando R, Brain T, Sohal SS, Cook AL, Guven N, Kunde D, Spring K, Eri R. Characterisation of colonic dysplasia-like epithelial atypia in murine colitis. World J Gastroenterol 2016; 22(37): 8334-8348
URL: https://www.wjgnet.com/1007-9327/full/v22/i37/8334.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i37.8334