Etiology of chronic liver diseases in the Northwest of Italy, 1998 through 2014

Table 4 Subgroup analysis hepatitis C virus etiology

Subgroup	Period	Patients, n	HCV (interaction P = 0.407)		HCV alone (interaction P = 0.252)
			n (%)	OR (95%CI)	n (%)	OR (95%CI)
Age < 50 yr	1998-2000 (Ref)	132	68 (52)	1	61 (46)	1
	2001-2003	114	53 (46)	0.80 (0.48-1.32)	35 (31)	0.51 (0.30-0.86)
	2004-2006	155	70 (45)	0.74 (0.46-1.18)	55 (35)	0.62 (0.38-1.00)
	2012-2014	111	45 (41)	0.55 (0.32-0.93)	37 (33)	0.52 (0.30-0.89)
Age ≥ 50 yr	1998-2000 (Ref)	163	89 (55)	1	60 (37)	1
	2001-2003	137	74 (54)	0.96 (0.61-1.52)	52 (38)	1.03 (0.64-1.65)
	2004-2006	181	70 (39)	0.51 (0.33-0.79)	57 (31)	0.77 (0.49-1.20)
	2012-2014	170	59 (35)	0.46 (0.30-0.72)	50 (29)	0.75 (0.47-1.19)

ORs were estimated by a logistic model including an interaction between the variables age and period. HCV: Hepatitis C virus.