Different pre-S deletion patterns and their association with hepatitis B virus genotypes

Table 2 Clinical and virological characteristics of hepatitis B virus carriers with pre-S deletion n (%)

Features	HBV/B(n = 43)	HBV/C(n = 43)	P value
Age (mean ± STD)	44.5 ± 8.8	45.8 ± 7.6	0.464
Male	33 (76.7)	31 (72.1)	0.805
HBV DNA ≥ 105 copies/mL	29 (67.4)	32 (74.4)	0.635
BCP mutation (A1762T, G1764A)	30 (69.8)	37 (86.0)	0.117
PC mutation (G1896A)	38 (88.4)	25 (58.1)	0.003
Clinical categories
ASC	2 (4.7)	2 (4.7)	1.000
Progressive liver diseases	41 (95.3)	41 (95.3)
CH	9 (20.9)	11 (25.6)	0.799
LC	8 (18.6)	14 (32.6)	0.216
NC-HCC	14 (32.6)	4 (9.3)	0.015
LC-HCC	10 (23.3)	12 (27.9)	0.805

ASC: Asymptomatic carriers; CH: Chronic hepatitis; HBV: Hepatitis B virus; LC: Liver cirrhosis; LC-HCC: Liver cirrhotic hepatocellular carcinoma; NC-HCC: Noncirrhotic hepatocellular carcinoma; BCP: Basal core promoter; PC: Precore.