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©The Author(s) 2016.
World J Gastroenterol. Sep 21, 2016; 22(35): 8041-8049
Published online Sep 21, 2016. doi: 10.3748/wjg.v22.i35.8041
Published online Sep 21, 2016. doi: 10.3748/wjg.v22.i35.8041
Table 1 Characteristics of the study population classified according to the presence of pre-S deletion n (%)
| Features | wild type pre-S(n = 147) | Pre-S deletion(n = 126) | P value |
| Age (mean ± STD) | 45.4 ± 6.6 | 45.9 ± 7.0 | 0.540 |
| Male | 101 (68.7) | 100 (79.4) | 0.054 |
| Genotype C | 42 (28.6) | 60 (47.6) | 0.003 |
| Genotype B | 94 (63.9) | 62 (49.2) | |
| Mixed genotypes | 11 (7.5) | 4 (3.2) | |
| HBV DNA ≥ 105 copies/mL | 67 (45.7) | 92 (73.0) | < 0.001 |
| BCP mutation (A1762T, G1764A) | 80 (54.4) | 98 (77.8) | < 0.001 |
| PC mutation (G1896A) | 87 (59.2) | 86 (68.3) | 0.132 |
| Clinical categories | |||
| ASC | 51 (34.7) | 4 (3.2) | |
| Progressive liver diseases | 96 (65.3) | 122 (96.8) | < 0.001 |
| CH | 24 (16.3) | 31 (24.6) | 0.098 |
| LC | 19 (12.9) | 36 (28.6) | 0.001 |
| NC-HCC | 29 (19.7) | 24 (19.0) | 1.000 |
| LC-HCC | 24 (16.3) | 31 (24.6) | 0.098 |
- Citation: Chen BF. Different pre-S deletion patterns and their association with hepatitis B virus genotypes. World J Gastroenterol 2016; 22(35): 8041-8049
- URL: https://www.wjgnet.com/1007-9327/full/v22/i35/8041.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i35.8041