Effects of Lizhong Tang on gastrointestinal motility in mice

Figure 7 Lizhong Tang extract ameliorated cisplatin-induced delays in gastric emptying. After a 24 h fast, the animals (n = 6/each group) were orally administered the indicated dosages of the Lizhong Tang extract, 5 mg/kg of a 5-HT₄ receptor agonist (mosapride), 5 mg/kg of a dopamine receptor antagonist (domperidone), or distilled water (DW; control). The Lizhong Tang pretreatment prevented the cisplatin-induced gastric emptying (GE) delay. The GE percentages were calculated as described in the Materials and Methods. The bars represent mean values ± SE. ^bP < 0.01; significantly different from the normal controls. Mosa: Mosapride; Dom: Domperidone; i.p: Intraperitoneally.