Tumor necrosis factor-α -G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients

Figure 3 Frequency of each tumor necrosis factor α -308 genotype in early and late hepatitis C virus fibrosis patients. Genotyping of TNFα -G308A was conducted in 120 chronic HCV patients (F0-F4) using PCR-RFLP analysis. The frequency of each genotype (GG, GA, AA) was calculated as percentage and compared in early (F0-F2, n = 60) and late (F2-F4, n = 60) HCV fibrosis patients. TNFα: Tumor necrosis factor alpha; HCV: Hepatitis C virus; RFLP: Restriction fragment length polymorphism.