Tumor necrosis factor-α -G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients

Figure 2 Distribution of tumor necrosis factor α -G308A polymorphism in hepatitis C virus infected patients with different fibrosis grade (F0-F4). Genotyping of TNFα -G308A was conducted for 120 chronic HCV patients (F0-F4) using PCR-RFLP analysis. The different TNFα -G308A genotypes were represented as percentages and compared among HCV patients with different fibrosis grades: F0 (n = 30), F1 (n = 30), F2-F3 (n = 30), F4 (n = 30). TNFα: Tumor necrosis factor alpha; HCV: Hepatitis C virus; RFLP: Restriction fragment length polymorphism.