Impact of Helicobacter pylori on the healing process of the gastric barrier

Figure 8 Helicobacter pylori lipopolysaccharide-driven inhibition of signal transducer and activator of transcription 3 phosphorylation and epidermal growth factor production. A: The impact of Helicobacter pylori or E. coli lipopolysaccharide (LPS) on the secretion of epidermal growth factor (EGF) by AGS cells; B: the percentage of phospho-signal transducer and activator of transcription 3 (phosphoSTAT3) in AGS cells measured by cell-based ELISA. Cells treated with EGF (0.125 ng/mL) were used as a positive control. The cut-off value was related to the response of untreated cells. The data represent the average values of four independent experiments. Statistically significant differences are indicated as ^aP < 0.05 vs untreated cells.