Haemoxygenase modulates cytokine induced neutrophil chemoattractant in hepatic ischemia reperfusion injury

Figure 8 Effect of Haemoxygenase inhibition and induction on Venular neutrophil adhesion in early phase of hepatic ischemia reperfusion. A: Venular neutrophil adhesion early phase; B: Sinusoidal neutrophil adhesion early phase. Significantly reduced venular neutrophil adhesion in preconditioned (RIPC + IRI) group compared to non-preconditioned group (IRI). HO inhibition in RIPC + IR showed significantly increased venular neutrophil adhesion. Values expressed as mean ± SE. Significantly reduced sinusoidal neutrophil adhesion in preconditioned group (RIPC + IRI) compared to non-preconditioned group (IRI). Values expressed as mean ± SE. HO: Haemoxygenase; IR: Ischemia reperfusion; RIPC: Remote ischemic preconditioning; IRI: Ischemia reperfusion injury.