Haemoxygenase modulates cytokine induced neutrophil chemoattractant in hepatic ischemia reperfusion injury

Figure 5 Effect of Haemoxygenase inhibition and induction on sinusoidal flow in early phase of hepatic ischemia reperfusion (A) and sinusoidal flow in late phase of hepatic ischemia reperfusion (B). Sinusoidal flow - V × (D/2) 2 ×π = V is velocity of RBC, D is sinusoidal diameter. Significantly better flow in preconditioned animals (RIPC + IRI) as compared to non-preconditioned (IR). HO inhibition significantly inhibits flow in preconditioned animals.Values expressed as mean ± SE. Sinusoidal flow - V × (D/2)2 ×π = V is velocity of RBC, D is sinusoidal diameter. Better flow in preconditioned animals (RIPC + IRI-24) as compared to non-preconditioned (IR-24). Values expressed as mean ± SE. HO: Haemoxygenase; IR: Ischemia reperfusion; RIPC: Remote ischemic preconditioning; IRI: Ischemia reperfusion injury.