Development of a human rotavirus induced diarrhea model in Chinese mini-pigs

Figure 5 Distribution of immunofluorescence specific to VP6 antigen of rotavirus in the intestine. The duodenum (A), jejunum (B) or ileum (C) from 5-d-old mock-impregnated control newborn mini-pigs and the duodenum (D), jejunum (E) or ileum (F) from HRV-incubated newborn mini-pigs at 24 hpi. No rotavirus antigen was detected at 24 hpi in any part of the small intestinal epithelium in mock-impregnated control newborn mini-pigs. The expression of rotavirus antigen in the ileum was significantly higher than in the jejunum in HRV-infected neonatal mini-pigs at 24 hpi. HRV: Human rotavirus.