Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity

Table 1 Inflammatory parameters in low dose 1% dextran sulfate sodium-induced colonic hypersensitivity model

	Water	DSS
Histological score	0.1 ± 0.1	4.0 ± 0.6b
MPO activity	2.4 ± 0.3	4.0 ± 0.6

On the same mouse, intestinal inflammation has been assessed by measuring the colonic myeloperoxidase (MPO) activity and histological score.

^bP < 0.01 Water vs dextran sulfate sodium (DSS) treated ANOVA 1 Way followed by Tuckey’s post-hoc test for multiple comparisons.