Mechanisms of drug resistance in colon cancer and its therapeutic strategies

doi:10.3748/wjg.v22.i30.6876

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 22, Issue 30

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (20091)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-2) series, Tables (1-2) series.

Item

Count

PDF

1707

WORD

387

HTML

14616

Figures (1-2)

344

Tables (1-2)

185

Sum=17239

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

1209

Download

1643

Sum=2852

Aug 14, 2016 (publication date) through Aug 29, 2024

Times Cited of This Article

Times Cited (259)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastroenterol. Aug 14, 2016; 22(30): 6876-6889
Published online Aug 14, 2016. doi: 10.3748/wjg.v22.i30.6876

Table 2 Potential agents to overcome resistance of cancer cells to apoptosis (non-exhaustive list)

Restoration of apoptotic signals		Alternative cell death		Ref.
BH3 mimetics	EGFR inhibitors	Autophagy inducers	Agents with p53-independent toxicity	Ref.
ABT-199 (venetoclax), ABT-263 (navitoclax), ABT-737, apogossypol, apogossypolone, gossypol, maritoclax, obatoclax, sabutoclax	Afatinib, cetuximab, dacomitinib, erlotinib, gefitinib, lapatinib, matuzumab, neratinib, nimotuzumab, panitumumab, zalutumumab	Clonidine, cryptotanshinone, curcumin, dihydrotanshinone, evodiamine, genistein, helenalin, monascuspiloin, oridonin, paclitaxel, quercetin, rapamycin, resveratrol, sodium valproate, verapamil	Betulinic acid, crocetin, cryptotanshinone, dihydrotanshinone, epigallocatechic-3-gallate, genistein, a-iso-cubebene, resveratrol, triptolide, thymoquinone, ursolic acid	[91,112-115,117,120,121,124,127-129,147-156]

EGFR: Epidermal growth factor receptor.

Citation: Hu T, Li Z, Gao CY, Cho CH. Mechanisms of drug resistance in colon cancer and its therapeutic strategies. World J Gastroenterol 2016; 22(30): 6876-6889
URL: https://www.wjgnet.com/1007-9327/full/v22/i30/6876.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i30.6876