Radiotherapy as valid modality for hepatocellular carcinoma with portal vein tumor thrombosis

Table 1 Systematic meta-analyses evaluating the efficacy of radiotherapy in hepatocellular carcinoma

Ref.	Subject	Study aim	n	CR OR	P value	3 yr OS OR	P value
Meng et al[24]	5 RCT, 12 CCT	TACE + RT vs TACE	1370	2.58	< 0.001	2.75	< 0.001
Liao et al[25]	10 RCT, 18 non-RCT	TACE + RT vs TACE	1223	-	-	2.53	0.001
Huo et al[30]	11 RCT, 14 non-RCT	TACE + RT vs TACE	2577	2.73	< 0.001	1.91	< 0.001
	PVTT subgroup		-	2.38	< 0.001	2.22	< 0.001

CCT: Non-randomized controlled clinical trial; CR: Complete response; OS: Overall survival; PVTT: Portal vein tumor thrombosis; RCT: Randomized controlled trial; TACE: Trans-arterial chemoembolization. RT: Radiotherapy technique.