Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid

Figure 2 Fluorescence spectra of various kinds of gastric cancer cell lines after treatment with 5-aminolevulinic acid and excitation with 405-nm light. A: MKN-7, derived from a well differentiated gastric cancer; B: MKN-74, derived from a moderately differentiated gastric cancer; C: MKN-45, derived from a poorly differentiated gastric cancer; D: Kato-III, derived from a signet-ring cell carcinoma; E: NIH-3T3, a non-cancerous fibroblast-like cell line. Each cell line was incubated with 1 mmol/L 5-ALA for 30 min. The conditions of spectral acquisition were equivalent among all samples. Spectra were measured with the MCPD-7000 spectral analytical system (Otsuka Electronics, Co., Ltd., Osaka, Japan).