How to predict clinical relapse in inflammatory bowel disease patients

Table 2 C-reactive protein as predictor of relapse in inflammatory bowel diseases patients

	No. Pt	No. R	Relapse rate	Mean CRP values R	Mean CRP values NR	P value
Brignola et al[5], 1986
CD	41	17	41%	2.2 mg/dL	0.7 mg/dL	0.010
Tibble et al[66], 2000
CD	43	25	58%	13.1 mg/L	9.1 mg/L	0.100
UC	37	19	51%	3 mg/L	9.7 mg/L	0.400
Bitton et al[15], 2001
UC	74	27	36.5%	0.08 mg/dL	0.25 mg/dL	NS
Costa et al[67], 2005
CD	38	15	39%	8 mg/L	6 mg/L	0.373
UC	41	19	46%	5 mg/L	4.5 mg/L	0.450
D'Incà et al[65], 2008
CD	65	20	31%	5.49 mg/L	3.13 mg/L	0.050
UC	97	37	38%	3.15 mg/L	3.08 mg/L	0.690
García-Sánchez et al[69], 2010
CD	66	18	27%	4.6 mg/L	5.6 mg/L	0.790
UC	69	21	31%	3.8 mg/L	1.7 mg/L	0.060
Kallel et al[62], 2010
CD1	53	10	18.9%	34 mg/L	4 mg/L	< 0.001
Naismith et al[70], 2014
CD	45	5	11%	2	2.1	0.539

¹Small bowel CD patients excluded. R: Relapsers; NR: Non relapsers; CRP: C reactive protein; CD: Crohn’s disease; UC: Ulcerative Colitis; IBD: Inflammatory bowel diseases.