Epidemiology of functional gastrointestinal disorders in infants and toddlers: A systematic review

doi:10.3748/wjg.v22.i28.6547

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Jul 28, 2016; 22(28): 6547-6558
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6547

Table 2 Prevalence or frequency of functional gastrointestinal disorders: Eating and feeding problems in infants and toddlers

Author, year, country	Study design, setting	Sample size (participation %)	Age bracket	Case definition	Case ascertainment	Score	FGID prevalence %
Author, year, country	Study design, setting	Sample size (participation %)	Age bracket	Case definition	Case ascertainment	Score	Regurgitation	Rumination	Cyclic vomiting
Van Tilburg, 2015, United States	Cross-sectional, community	264 (82.5)	0-3 yr	Rome III	Online panel w/mothers	2	25.9	4.3	3.4
					QPGS-RIII
					PedsQL4.0
Rouster, 2015, United States	Cross-sectional, specialty care	332 (91.0)	0-4 yr	Rome III	Parental interviews	4	13.2	3.0	10.2
Rouster, 2015, United States	Cross-sectional, specialty care	332 (91.0)	0-4 yr	Rome III	QPGS-RIII	4	13.2	3.0	10.2
Liu, 2009, China	Cross-sectional, community	5030 (99.4)	0-2 yr	Rome III	Parental interviews	6	17.9
Liu, 2009, China	Cross-sectional, community	5030 (99.4)	0-2 yr	Rome III	Parental questionnaire on GI symptoms	6	17.9
Primavera, 2009, Italy	Cross-sectional, primary care	9291 (NR)	0-14 yr	Rome II	Interviews w/parents and children	4	0.44
Primavera, 2009, Italy	Cross-sectional, primary care	9291 (NR)	0-14 yr	Rome II	FGID questionnaire	4	0.44
Campanozzi, 2009, Italy	Cross-sectional, primary care	2642 (NR)	1-12 mo	Rome II	Interviews w/parents and children	4	12.0
Campanozzi, 2009, Italy	Cross-sectional, primary care	2642 (NR)	1-12 mo	Rome II	I-GERQ	4	12.0
Miele, 2004, Italy	Cross-sectional, primary care	9660 (NR)	1-12 mo	Rome II	Interviews w/parents and children	4	0.74
Miele, 2004, Italy	Cross-sectional, primary care	9660 (NR)	1-12 mo	Rome II	FGID questionnaires	4	0.74

Score = Methodological strength of study (maximum 8) by Loney’s criteria. PedsQL4.0: Pediatric Quality of Life version Inventory 4.0; I-GERQ: Infant Gastroesophageal Reflux Questionnaire; QPGS-RIII: Questionnaire on Pediatric Gastrointestinal Symptoms - Rome III; FGD: Functional gastrointestinal disorders; NR: Not reported; w: With; GI: Gastrointestinal.

Citation: Ferreira-Maia AP, Matijasevich A, Wang YP. Epidemiology of functional gastrointestinal disorders in infants and toddlers: A systematic review. World J Gastroenterol 2016; 22(28): 6547-6558
URL: https://www.wjgnet.com/1007-9327/full/v22/i28/6547.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i28.6547