Copyright
©The Author(s) 2016.
World J Gastroenterol. Jul 28, 2016; 22(28): 6520-6526
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6520
Published online Jul 28, 2016. doi: 10.3748/wjg.v22.i28.6520
SNP | Risk allele | HWE (control), P value | Inheritance model | Genotype | Control | Gastric cancer | OR (95%CI)1 | P value1 |
rs7903146 | T | 0.741 | n = 129 | n = 122 | ||||
CC | 73 (56.6) | 56 (45.9) | 1 | |||||
Codominant | CT | 49 (38.0) | 48 (39.3) | 1.30 (0.75–2.25) | 0.345 | |||
TT | 7 (5.4) | 18 (14.8) | 3.61 (1.36–9.61) | 0.010 | ||||
Dominant | CC | 73 (56.6) | 56 (45.9) | 1 | ||||
CT + TT | 56 (43.4) | 66 (54.1) | 1.58 (0.94–2.64) | 0.082 | ||||
Recessive | CC + CT | 122 (94.6) | 104 (85.2) | 1 | ||||
TT | 7 (5.4) | 18 (14.8) | 3.11 (1.22–7.92) | 0.017 | ||||
rs12255372 | T | 0.053 | n = 129 | n = 117 | ||||
GG | 85 (65.9) | 78 (66.7) | 1 | |||||
Codominant | GT | 35 (27.1) | 32 (27.3) | 1.06 (0.59–1.92) | 0.841 | |||
TT | 9 (7.0) | 7 (6.0) | 1.11 (0.38–2.25) | 0.849 | ||||
Dominant | GG | 85 (65.9) | 78 (66.7) | 1 | ||||
GT + TT | 44 (34.1) | 39 (33.3) | 1.06 (0.61–1.83) | 0.839 | ||||
Recessive | GG + GT | 120 (93.0) | 110 (94.0) | 1 | ||||
TT | 9 (7.0) | 7 (6.0) | 1.02 (0.36–2.90) | 0.972 |
- Citation: Torres K, Labrador L, Valderrama E, Chiurillo MA. TCF7L2 rs7903146 polymorphism is associated with gastric cancer: A case-control study in the Venezuelan population. World J Gastroenterol 2016; 22(28): 6520-6526
- URL: https://www.wjgnet.com/1007-9327/full/v22/i28/6520.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i28.6520