Re-evaluation of classical prognostic factors in resectable ductal adenocarcinoma of the pancreas

Table 4 Porto-mesenteric vein resection and survival

Ref.	Year	n	VR rate (%)	Median OS without VR/with VR (mo)	Survival model	HR (95%CI)	P value
Jeong et al[39]	2015	276	46 (17)	16/12	Multivariable	1.15 (0.78–1.71)	0.474
Murakami et al[66]	2015	937	435 (46)	26/19	Multivariable	1.16 (0.89-1.53)	0.268
Wang et al[67]	2014	122	64 (53)	31/18	Multivariable	NR	NS
Kelly et al[68]	2013	492	70 (14)	19/12	Multivariable	1.14 (0.83-1.57)	0.410
Gong et al[69]	2013	566	119 (21)	20/13	Univariable	NR	< 0.050
Castleberry et al[70]	2012	3582	281 (8)	Increased 30-d postoperative mortality, 2.9% vs 5.7%	Multivariable	2.1 (1.22-3.73)	0.008
Chakravarty et al[71]	2010	87	12 (14)	10/9	Multivariable	NR	0.591
Ouaissi et al[72]	2010	149	59 (40)	19/18	Multivariable	DFS: 0.43 (0.22-0.82)	0.011
Kaneoka et al[49]	2009	84	42 (50)	26/12	Multivariable	NR	NS
Kurosaki et al[73]	2008	77	35 (45)	20/20	Univariable	NR	0.330
Fukuda et al[30]	2007	121	37 (31)	NR	Univariable	NR	0.550
Carrère et al[74]	2006	133	45 (34)	19/15	Univariable	NR	0.690
Shimada et al[75]	2006	149	86 (58)	35/14	Multivariable	2.25 (1.09–3.62)	NR
Tseng et al[76]	2004	291	110 (38)	27/23	Multivariable	1.13 (0.79-1.63)	0.500
Poon et al[77]	2004	50	12 (24)	21/20	Univariable	NR	0.769
Nakagohri et al[78]	2003	81	33 (41)	10/15	Univariable	NR	NS
Bachellier et al[79]	2001	87	31 (36)	12/12	Univariable	NR	0.480

OS: Overall survival; PALN: Para-aortic lymph node involvement; NS: Not significant.