Re-evaluation of classical prognostic factors in resectable ductal adenocarcinoma of the pancreas

Table 2 Prognostic relevance of lymph node ratio

Ref.	Year	n	Cut-off	Detection rate (%)	Median OS with highest LNR (mo)	Survival model	HR (95%CI)	P value
Fouquet et al[34]	2014	166	0.2	76 (46)	NR	Multivariable	2.38 (1.4-4.0)	0.001
Dusch et al[21]	2014	415	Continuous	0.10 (0-0.81)1	NR	Multivariable	1.73 (NR)	0.002
Valsangkar et al[57]	2013	14907	0.3	4038 (27)	NR	Multivariable	2.27 (1.67-3.08)	< 0.001
Lewis et al[58]	2013	424	0.3	83 (20)	16	Multivariable	1.97 (NR)	< 0.001
Robinson et al[59]	2012	131	0.15	70 (53)	NR	Multivariable	4.14 (NR)	< 0.010
La Torre et al[60]	2011	101	0.2	30 (30)	13	Multivariable	4.88 (1.07-22.2)	0.008
Bhatti et al[46]	2010	84	0.3	26 (31)	6	Multivariable	2.7 (1.6–4.4)	0.010
Riediger et al[61]	2009	182	0.3	32 (18)	NR	Multivariable	2.2 (1.4-3.6)	< 0.001
Slidell et al[22]	2008	3868	0.4	602 (16)	10	Multivariable	1.82 (1.59-2.07)	< 0.001
Pawlik et al[6]	2007	905	0.4	154 (17)	12	Multivariable	2.55 (1.75-2.70)	0.001

¹Mean (range). LNR: Lymph node ratio; OS: Overall survival.