Benefits and harms of endoscopic screening for gastric cancer

Table 1 Comparison of results from cohort studies of endoscopic screening for gastric cancer

Author	Riecken et al[9]	Matsumoto et al[10]	Hosokawa et al[11]	Hamashima et al[12]	Hamashima et al[13]
Publication	2002	2007	2011	2015	2015
Country	China	Japan	Japan	Japan	Japan
Target age, yr	35-64	≥ 40	Average: 50.0	40-79	40-79
Follow-up, yr		9	5	5	6
Number of subjects	4364	7178	18011	16373	9950
Comparators	-	-	Radiographic screening	-	Radiographic screening
Number of comparators	-	-	36870	-	4324
Outcome indicators	SMR	SMR	Hazard ratio (HR)	SMR	Relative risk
Main results	1.01	Male: 0.71	HR = 0.15	0.43	Adjusted RR2
	(95%CI: 0.72-1.37)	(95%CI: 0.33-1.10)	(95%CI: 0.05-0.50)	(95%CI: 0.30-0.57)	0.327
		Female: 0.62	Adjusted HR1 = 0.23		(95%CI: 0.118-0.908)
		(95%CI: 0.19-1.05)	(95%CI: 0.07-0.76)

¹Adjusted HR by sex and age;

²Adjusted RR by sex, age group, and resident city. SMR: Standard mortality ratio; CI: Confidence interval; HR: Hazard ratio; RR: Relative risk.