Serum metabolome profiles characterized by patients with hepatocellular carcinoma associated with hepatitis B and C

Figure 3 Serum concentrations of glutamic acid (A), methionine (B) and γ-glutamyl-glycine-glycine (C) in hepatitis B virus-related hepatocellular carcinoma and hepatitis C virus-related hepatocellular carcinoma. The multiple logistic regression model using these three metabolites demonstrated that they had a significant ability to discriminate between HCC-B and HCC-C (D). ^aP < 0.05, ^cP < 0.01, ^eP < 0.0001 between groups. Glu: Glutamic acid; Met: Methionine; γ-Glu-Gly-Gly: γ-glutamyl-glycine-glycine; MLR: Multiple logistic regression; HCC-B: Hepatitis B virus-related HCC; HCC-C: Hepatitis C virus-related HCC; HCC: Hepatocellular carcinoma.