Favorable lifestyle before diagnosis associated with lower risk of screen-detected advanced colorectal neoplasia

Table 3 Risk of advanced colorectal neoplasia by the lifestyle score n (%)

	Total (n = 6315) % column1	Advanced colorectal neoplasia(n = 311), n	Absolute risk estimates per 10004	OR, (95%CI)2	P trend5
Lifestyle score3					< 0.001
0-1	371 (6)	32	86.3	1.00 (Ref)
2	1248 (20)	92	73.7	0.82 (0.45-1.16)
3	1749 (27)	71	40.6	0.43 (0.28-0.73)
4	1312 (21)	46	35.1	0.41 (0.23-0.64)
5-6	684 (11)	21	30.7	0.41 (0.22-0.73)
Mising	951 (15)	49
C-statistics				0.71 (0.68-0.74)

¹The number of replies may not sum to the total due to incomplete replies on the lifestyle questionnaire;

²The model was adjusted for age (continuously), screenings arm (fecal immunochemical test, flexible sigmoidoscopy), gender (women, men), center (Moss, Bærum), education (primary school, high school, university/college studies of minimum 2 years) and whole meal bread;

³One point for each lifestyle adherence, except only 1 point if adherence to both: fatty fish and fruits and vegetables;

⁴Absolute risk calculated: with in each score: (n ACN/Total n)*1000;

⁵P trend was calculated using the lifestyle score as continuous. Lifestyle score characteristics, odds ratio (OR) and 95%CI for the risk of advanced colorectal neoplasia by multivariable logistic regression for participants in the lifestyle sub-study of the Bowel Cancer Screening in Norway - a pilot study.