Effect of dietary vitamin C on gastric cancer risk in the Korean population

Table 3 ORs and 95%CIs of gastric cancer by tertiles of dietary vitamin C

	Range (mg/d)	No. ofcontrols/cases	Model IOR (95%CI)	Model IIOR (95%CI)	Model IIIOR (95%CI)
Total (n = 1245)
T1	< 80.14	276/186	1	1	1
T2	80.14-120.67	277/130	0.70 (0.53-0.92)	0.81 (0.59-1.10)	0.81 (0.58-1.12)
T3	≥ 120.67	277/99	0.53 (0.40-0.71)	0.64 (0.46-0.88)	0.71 (0.50-1.00)
P for trend1			< 0.001	0.007	0.052
Men (n = 810)
T1	< 73.18	180/107	1	1	1
T2	73.18-110.59	180/93	0.87 (0.62-1.23)	1.11 (0.75-1.64)	1.07 (0.70-1.61)
T3	≥ 110.59	180/70	0.65 (0.45-0.94)	0.78 (0.52-1.18)	0.91 (0.59-1.41)
P for trend			0.022	0.229	0.659
Women (n = 435)
T1	< 91.70	96/69	1	1	1
T2	91.70-139.52	97/45	0.65 (0.40-1.03)	0.81 (0.48-1.36)	0.85 (0.49-1.48)
T3	≥ 139.52	97/31	0.45 (0.27-0.74)	0.57 (0.32-1.00)	0.61 (0.34-1.12)
P for trend			0.002	0.051	0.109

¹Trends were calculated using the median intake for each dietary vitamin C category as a continuous variable: Model I: Unadjusted; Model II: Adjusted by first-degree family history of gastric cancer, education level, job, household income, smoking status, regular exercise; Model III: Additionally adjusted for H. pylori infection.