Increased duodenal expression of miR-146a and -155 in pediatric Crohn’s disease

Figure 1 Expression of microRNA-146a (A), microRNA-155 (B) and microRNA-122 (C) in the duodenal mucosa of pediatric patients with Crohn’s disease. Expression of microRNA (miR)-146a was significantly higher in the inflamed duodenal mucosa of children with Crohn’s disease (CD) compared to the intact mucosa and controls. miR-155 showed significantly elevated expression in the inflamed region of the duodenum compared to the control group. There was no significant difference in the expression of miR-122 between the groups. ^aP≤ 0.05 vs Control; ^bP≤ 0.001 vs Control; ^dP≤ 0.01 vs CD intact.