Gut dysfunction in Parkinson's disease

doi:10.3748/wjg.v22.i25.5742

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Jul 7, 2016 (publication date) through Feb 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2016; 22(25): 5742-5752
Published online Jul 7, 2016. doi: 10.3748/wjg.v22.i25.5742

Table 5 Constipation and defecatory dysfunction

Mechanism	Evaluation	Treatment
Slow transit constipation	Radiopaque marker study for colonic transit	High fiber diet, psyllium, proper fluid intake
	Wireless motility capsule	Adjustment of anticholinergics and dopaminergic agents
		Macrogol¹
		Lubiprostone²
Dyssynergic defecation	Anorectal manometry	Biofeedback therapy
	Rectal balloon expulsion	Botulinum neurotoxin injection into the puborectalis
	Defecography

¹Macrogol-polyethylene glycol (an osmotic laxative);

²Lubiprostone-chloride channel activator (increases fluid secretion in the intestine).

Citation: Mukherjee A, Biswas A, Das SK. Gut dysfunction in Parkinson's disease. World J Gastroenterol 2016; 22(25): 5742-5752
URL: https://www.wjgnet.com/1007-9327/full/v22/i25/5742.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i25.5742