miR-422a is an independent prognostic factor and functions as a potential tumor suppressor in colorectal cancer

Figure 2 Kaplan-Meier curves for overall survival in 102 colorectal cancer patients based on miR-422a expression and the change of miR-422a expression compared to adjacent normal mucosa, respectively. Results showed that patients with low miR-422a expression had a significantly poorer prognosis than those with high miR-422a expression (A) (P = 0.0028), and patients with decreased miR-422a expression compared to adjacent normal mucosa had a significantly poorer prognosis than those with increased miR-422a expression (B) (P < 0.001).