Intravoxel incoherent motion diffusion-weighted imaging for monitoring chemotherapeutic efficacy in gastric cancer

Figure 5 Calculated maps of intravoxel incoherent motion diffusion-weighted imaging parameters and the histopathological images. A: The lower ADC (0.521 × 10^-3 mm²/s) and D values (0.475 × 10^-3 mm²/s) and the higher f (40.92%) and D* (0.131 mm²/s) values, which correspond to low necrosis (10%) and cellular apoptosis (7%) and high MVD (36) in the control group; B: Increased ADC (0.875 × 10^-3 mm²/s) and D (0.851 × 10^-3 mm²/s) values and reduced f (17.20%) and D^* (0.098 mm²/s) values, which correspond to the increased necrosis (18%) and cellular apoptosis (23%) and decreased MVD (17) in the 3-d treatment group. Note high signal intensity within tumor suggesting necrosis. asterisk means necrosis area; The triangle symbol means skin of the mouse. ADC: Apparent diffusion coefficient; MVD: Microvessel density.