Comprehensive mutation screening for 10 genes in Chinese patients suffering very early onset inflammatory bowel disease

Table 3 Comparison of features between patients with mutations and polymorphisms

	Group 1	Group 2
Size of sample	5	8
Age of onset (mo)	2.7	7.7
Height percentile	5.0%	15.6%
Weight percentilea	1.0%	27.5%
WBC (× 10-9)	15.2	16.3
Hemoglobin (g/L)a	87.4	108.5
Platelets (× 10-9)	538.4	424.0
C reactive protein (mg/L)	60.7	35.9
ESR (mm/H)	32.2	16.6
TNFα (pg/mL)	44.5	51.6
Diagnosis of CD	100.0%	62.5%
Recurrent infection	80.0%	25.0%
Perianal disease	60.0%	25.0%

^aP < 0.05. All measurement data are expressed as mean. Group 1: Mutations in IL-10RA or IL-10RB; Group 2: Polymorphisms. Height and weight percentile was calculated according to WHO charts. WBC: White blood cell; ESR: Erythrocyte sedimentation rate; TNFα: Tumor necrosis factor alpha; CD: Crohn's disease.