Current status of intragastric balloon for obesity treatment

Table 1 Types of intragastric balloons

Balloon	Material	Volume	Weight loss1	Note
Fluid-supplied
Orbera (Apollo Endosurgery)	Silicone	400-700 mL (saline)	16.9 ± 0.9 kg (at 6 mo)[58]	Most widely used and studied intragastric balloon
				Volume adjustment at the time of placement
Spatz Adjustable Balloon system (Spatz FGIA)	Silicone	400-600 mL (saline)	24 kg (at 12 mo)[64]	Totally adjustable balloon
				Approved for 12 mo of implantation
ReShape Duo® Integrated DualBalloon System (ReShape medical)	Silicone	900 mL (450 mL × 2) (saline)	25.1 ± 1.6 %EWL (at 6 mo)[62]	Two independent balloons connected to silicone shaft
The Elipse™ (Allurion Technologies)	N/A	450-550 mL (filling fluid)	2.4 kg (at 6 wk)[19]	Naturally swallowed, self-emptying, and naturally excreted
Air-supplied
Obalon® Gastric Balloon (Obalon Therapeutics)	N/A	250 mL (air, nitrogen)	5 kg (at 12 wk)[66]	Can be swallowed
				A second or a third balloon can be swallowed depending on patient’s progress
Heliosphere BAG® (Helioscopie)	Polyurethane and silicone	950 mL (air)	16 ± 7 kg (at 6 mo)[23]	Less than 30 g

¹Values extrapolated from representative reviews and clinical trials of each intervention. N/A: Not available; %EWL: Percentage of excess weight loss.