MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737

Figure 4 Restoration of Tg737 rescues the miR-548a-5p induced cell proliferation inhibition and apoptosis induced by cisplatin. A: Western blot was performed 48 h after transfection of pc CON, pc Tg737 and plasmid with 3’UTR of Tg737 into miR-548a-5p overexpressing HepG2 and MHCC97H cells; B: CCK-8 assay; C: Colony forming assay; D: Cell cycle assay; E: Cell apoptosis increased in anti-miR-548a-5p transfected HepG2 and MHCC97H cells; F: Cell apoptosis decreased in miR-548a-5p transfected HepG2 and MHCC97H cells. ^aP < 0.05, ^bP < 0.01 vs control.