MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737

Figure 3 miR-548a-5p promotes hepatocellular carcinoma cell proliferation in vitro and in vivo. A: CCK-8 assays of HepG2 and MHCC97H cells constantly expressing miR-548a-5p or miR-control; B: Colony forming assays of HepG2 and MHCC97H cells constantly expressing miR-548a-5p or miR-control; C: Cell cycle assays of HepG2 and MHCC97H cells constantly expressing miR-548a-5p or miR-control; D: MiR-548a-5p or miR-control overexpressing HepG2 cells were injected into the subcutaneous layer of nude mice. The mice were killed 30 d after injection; E: Tumor volumes and weight. ^aP < 0.05, ^bP < 0.01 vs control.