MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737

Figure 1 Down-regulation of Tg737 accelerates hepatocellular carcinoma cell proliferation. A: Western blot analysis of Tg737 expression in HepG2 and MHCC97H cells transfected with si-Tg737 or negative control (si-control); B: Impact of Tg737 down-regulation on HCC cell proliferation detected by CCK-8 assay after si-Tg737 and si-control transfection in HepG2 and MHCC97H cell lines; C: Impact of Tg737 down-regulation on colony forming ability of HepG2 and MHCC97H cell lines. The relative percentage of colony numbers from the si-Tg737 group is given as 100%; D: Cell cycle assay of HepG2 and MHCC97H cells transfected with si-Tg737 and si-control. The charts were illustrated by the percentage of cells in the G0/G1, S, and G2/M phase of cell cycle, respectively. ^aP < 0.05, ^bP < 0.01 vs control.