Visceral hypersensitive rats share common dysbiosis features with irritable bowel syndrome patients

Figure 4 Primary component analysis and cluster analysis by time points. Primary components were calculated from the relative abundance of all 2413 OTUs. A: The percentage of variances explained by the first 20 primary components. The primary component was separately plotted at week 3 (B), week 8 (C), and week 12 (D). The cluster analysis divided the samples into three clusters, and the samples in the same cluster were connected together. The ellipse was estimated to cover 75% of dots in this cluster. Each cluster was named according to the samples involved in this cluster. The MS group formed isolated clusters, indicated as “MS cluster”, at week 3 and week 12. MS: Maternal separation; PCA: Primary component analysis.