Usefulness of portal vein pressure for predicting the effects of tolvaptan in cirrhotic patients

Figure 1 Effects of tolvaptan on liquid retention in all of the patients included in this study. A: Box and whisker plots of daily urine volumes during the first week of tolvaptan administration in all of the patients. Median values were 1108 mL, 1600 mL, 1500 mL and 1582 mL on day 0, 1, 3 and 7, respectively; B: Box and whisker plots of changes in body weight from baseline during the first week of tolvaptan administration in all of the patients. Median changes in body weight were -1 kg, -1.2 kg, and -1.3 kg on day 1, 3 and 7, respectively. Difference between day 0 (= baseline) and day1, 3 and 7 were compared by using Wilcoxon signed rank test.