Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model

Figure 4 Immunohistochemical staining of matrix metalloprotein 9 in hepatocellular carcinoma in group A (TACE + GRGDSP loaded nanoparticles), group B (Control group 1, TACE + GRGDSP) and group C (Control group 2, TACE alone) (magnification × 100). A: Immunohistochemical staining of MMP-9 in hepatocellular carcinoma in group A. B: Higher immunohistochemical expression of MMP-9 in hepatocellular carcinoma was observed in group B than in group A. C: Higher immunohistochemical expression of MMP-9 in hepatocellular carcinoma was observed in group C than in groups A and B. MMP-9: Matrix metalloprotein 9; TACE: Transarterial chemoembolization.