Interleukin-22 ameliorates acute severe pancreatitis-associated lung injury in mice

Figure 5 Real-time PCR analysis of expression of Bcl-2(A and D), Bcl-xL (B and D) and IL-22RA1 mRNAs (C and D) in lung tissue. Numbers of cases from each group statistically analyzed are 12 (Normal control), 9 (SAP 24 h), 8 (SAP 48 h), 8 (SAP 72 h), 8 (PBS) and 12 (rIL-22). Results are presented as mean ± SD. ^aP < 0.05 vs the normal control group, ^cP < 0.05 vs the PBS group. Bcl-2: B cell lymphoma/leukemia-2; Bcl-xL: B cell lymphoma/leukemia-extra large; IL-22RA1: Interleukin-22 receptor subunit alpha-1; PBS: Phosphate-buffered saline; rIL-22: Recombinant interleukin-22; STAT3: Signal transducer and activator of transcription 3.