Multiorgan chronic inflammatory hepatobiliary pancreatic murine model deficient in tumor necrosis factor receptors 1 and 2

Figure 2 Rearing and grooming rate changes and hindpaw mechanical threshold modification due to dibutyltin dichloride-treatments. A: Rearing and grooming rates significantly diminished in dibutyltin dichloride (DBTC)-treated animals vs the sham-administered animals and persisted throughout the study (P < 0.0001); B: Hindpaw withdrawal threshold response to mechanical stimuli in DBTC-treated animals (DBTC) had significant decreased vs sham-administered control (sham) mice (P < 0.0001). n = 5 animals/group.