Copyright
©The Author(s) 2016.
World J Gastroenterol. Jun 7, 2016; 22(21): 5122-5131
Published online Jun 7, 2016. doi: 10.3748/wjg.v22.i21.5122
Published online Jun 7, 2016. doi: 10.3748/wjg.v22.i21.5122
Study | Country | Study design | n(active: control) | Transit timeoutcome, method | Probiotic strain | Daily dosage(109 CFU) | Delivery method | Treatmentduration(d) |
Agrawal et al[14], 2009 | United Kingdom | Parallel groups | 17:17 | CTT, radiopaque markers | B. lactis DN-173 010 | 25 | Active: Yogurt + probiotic | 28 |
Control: Nonfermented milk-based product | ||||||||
Bartram et al[15], 1994 | Germany | Cross-over | 12 | OATT, radiopaque markers | B. longum | > 0.5 | Active: Yogurt with 2.5 g lactulose + probiotic | 21 |
Control: Yogurt | ||||||||
Bazzocchi et al[25], 2014 | Italy | Parallel groups | 19:12 | TITT, radiopaque markers | L. plantarum, L. acidophilus, L. rhamnosus, B. longum, B. breve | - | Active: Sachet with psyllium+probiotic | 56 |
Control: Sachet with 2.8 g maltodextrin | ||||||||
Bouvier et al[16], 2001 | France | Parallel groups | 36:36 | CTT, radiopaque markers | B. lactis DN-173 010 | 97.5 | Active: Probiotic fermented milk | 11 |
Control: Heat-treated probiotic fermented milk | ||||||||
Holma et al[17], 2010 | Finland | Parallel groups | 12:10 | TITT, radiopaque markers | L. rhamnosus GG | 20 | Active: Buttermilk + probiotic and white wheat bread | 21 |
Control: White wheat bread | ||||||||
Hongisto et al[18], 2006 | Finland | Parallel groups | 16:14 | TITT, radiopaque markers | L. rhamnosus GG | 15 | Active: Yogurt + probiotic and low fiber toast | 21 |
Control: Low fiber toast | ||||||||
Krammer et al[24], 2011 | Germany | Parallel groups | 12:12 | CTT, radiopaque markers | L. casei Shirota | 6.5 | Active: Probiotic fermented milk drink | 28 |
Control: Nonfermented milk drink | ||||||||
Magro et al[26], 2014 | Brazil | Parallel groups | 26:21 | CTT, radiopaque markers | L. acidophilus NCFM, B. lactis HN019 | 2 | Active: Yogurt + polydextrose + probiotic Control: Yogurt | 14 |
Malpeli et al[19], 2012 | Argentina | Cross-over | 83 | OCTT, carmine red dye | B. lactis BB12 | 2-20 | Active: Yogurt with 0.625 g inulin and oligofructose + probiotic | 15 |
L. casei CRL 431 | 2-12 | Control: Yogurt | ||||||
Marteau et al[20], 2002 | France | Cross-over | 32 | CTT, radiopaque markers | B. lactis DN-173 010 | 18.75 | Active: Yogurt + probiotic | 10 |
Control: Yogurt | ||||||||
Merenstein et al[27], 2014 | United States | Crossover | 68 | CTT, radiopaque markers | B. animalis ssp. lactis Bf-6 | 20-56 | Active: Yogurt + probiotic | 14 |
Control: Yogurt | ||||||||
Rosenfeldt et al[21], 2003a | Denmark | Cross-over | 13 | GTT, radiopaque markers | L. rhamnosus 19070-2 | 20 | Active: Freeze-dried powder + probiotic | 18 |
L. reuteri DSM 12246 | 20 | Control: Skimmed milk powder w/dextrose | ||||||
Rosenfeldt et al[21], 2003b | Denmark | Cross-over | 13 | GTT, radiopaque markers | L. casei subsp. alactus CHCC 3137 | 20 | Active: Freeze-dried powder + probiotic | 18 |
L. delbrueckii subsp. lactis CHCC 2329 | 20 | Control: Skimmed milk powder w/dextrose | ||||||
L. rhamnosus GG | 20 | |||||||
Sairanen et al[22], 2007 | Finland | Parallel groups | 22:20 | CTT, radiopaque markers | B. longum BB536, B. lactis 420 | 2.4-181 | Active: Probiotic fermented milk | 21 |
L. acidophilus 145 | 0.48 | Control: Fermented milk | ||||||
Tulk et al[28], 2013 | Canada | Crossover | 65 | GTT, carmine red/carbon black capsules | B. lactis Bb12, L. acidophilus La5, L. casei CRL431 | 2 | Active: Yogurt + probiotic + inulin | 15 |
Control: Yogurt | ||||||||
Waller et al[23], 2011a | United States | Parallel groups | 33:34 | WGTT; radiopaque markers | B. lactis HN019 | 1.8 | Active: Capsule, maltodextrin, probiotic | 14 |
Control: Capsule, maltodextrin | ||||||||
Waller et al[23], 2011b | United States | Parallel groups | 33:34 | WGTT; radiopaque markers | B. lactis HN019 | 17.2 | Active: Capsule, maltodextrin, probiotic | 14 |
Control: Capsule, maltodextrin |
- Citation: Miller LE, Zimmermann AK, Ouwehand AC. Contemporary meta-analysis of short-term probiotic consumption on gastrointestinal transit. World J Gastroenterol 2016; 22(21): 5122-5131
- URL: https://www.wjgnet.com/1007-9327/full/v22/i21/5122.htm
- DOI: https://dx.doi.org/10.3748/wjg.v22.i21.5122