Usefulness of portal vein pressure for predicting the effects of tolvaptan in cirrhotic patients

Table 1 Demographic and clinical characteristics at baseline

Characteristics	n = 40
Age (yr)	65 (40-82)
Gender (M/F)	26/14
Body weight (kg)	61.9 (44.8-88.5)
Liver disease etiology
Hepatitis B/Hepatitis C/Alcohol/PBC/PSC/NASH	3/15/15/3/1/3
Child-Pugh classification A/B/C	3/19/18
Total bilirubin (mg/dL)	1.0 (0.4-26.2)
Serum albumin (g/dL)	2.6 (1.6-3.7)
Serum creatinine (mg/dL)	0.95 (0.45-6.45)
Serum eGFR (mL/min/1.73 m2)	60 (8-112)
Serum sodium (mEq/L)	139 (124-146)
Serum hyaluronic acid (ng/mL)	420.7 (122-6984)
BUN (mg/dL)	19 (8.1-81.8)
Urine osmolality (mOsm/L)	414.5 (254-954)
Hepatic venous pressure gradient (mmH2O)1	240 (105-580)
Dose of furosemide (mg/d)	37.0 ± 29.5
Dose of spironolactone (mg/d)	43.4 ± 26.8
Hepatocellular carcinoma (with/without)	12/28
Esophageal varix (with/without)	25/15

¹Hepatic venous pressure gradient was measured in 24 patients. Categorical variables are given as number. Almost continuous variables are given as median (range). Dose of furosemide and spironolactone are given as mean ± SD). BUN: Blood urea nitrogen; PBC: Pimary biliary cirrhosis; PSC: Primary sclerosing cholangitis; NASH: Nonalcoholic steatohepatitis; eGFR: Estimated glomerular filtration rat.