Serum adipokines might predict liver histology findings in non-alcoholic fatty liver disease

Table 1 Clinico-demographic and laboratory data of the participants

Variable	Total	Simple fatty liver	Non-alcoholic steatohepatitis
	n = 54	n = 2	n = 28
Age (yr)	37.02 ± 9.82	27.00 ± 2.82	35.00 ± 8.47
Male gender, n (%)	35 (64.8)	2 (100)	17 (60.7)
Waist circumference (cm)	102.13 ± 2.69	101.00 ± 42.24	101.57 ± 2.71
Body mass index (kg/m2)	30.55 ± 3.97	28.09 ± 7.77	29.92 ± 3.79
Diabetes mellitus present, n (%)	12 (22.2)	0 (100)	11 (39.3)
Metabolic syndrome present, n (%)	36 (66.7)	1 (50)	21 (75)
Adiponectin (mg/L)	8.14 ± 2.91	8.20 ± 2.67	7.00 ± 0.28
Visfatin (ng/mL)	19.96 ± 17.5	5.40 ± 0.84	18.34 ± 16.18
Resistin (mg/mL)	2.51 ± 1.08	1.70 ± 1.83	2.10 ± 1.04
Hepcidin (ng/mL)	64.0 ± 0.62	48.50 ± 0.38	75.00 ± 0.49
Tumor necrosis factor-alpha (pg/mL)	2.68 ± 19.32	0.96 ± 9.05	3.68 ± 20.93
Interleukin 6 (pg/mL)	7.59 ± 5.75	4.70 ± 0.24	7.41 ± 4.78
Interleukin 8 (pg/mL)	27.41 ± 24.99	13.60 ± 13.01	38.60 ± 28.21
Alanine aminotransferase (U/L)	65.91 ± 36.11	37.00 ± 0.00	82.10 ± 39.25
Aspartate aminotransferase (U/L)	42.18 ± 20.48	25.00 ± 4.24	49.67 ± 24.14
Alkaline phosphatase (U/L)	181.50 ± 76.14	144.21 ± 42.41	180.23 ± 45.22
Gamma glutamyl transpeptidase (U/L)	54.12 ± 62.55	44.40 ± 30.54	55.40 ± 33.26
Fasting blood sugar (mg/dL)	98.41 ± 14.12	98.25 ± 16.31	103.0 ± 0.00
Insulin (mU/L)	15.16 ± 13.42	10.68 ± 3.65	17.40 ± 18.00
Triglyceride (mg/dL)	150.09 ± 70.18	60.20 ± 9.70	167.57 ± 77.19
Total cholesterol (mg/dL)	177.55 ± 34.17	165.85 ± 40.65	183.77 ± 37.76
Low density lipoprotein cholesterol (mg/dL)	100.89 ± 29.03	98.75 ± 35.42	103.15 ± 32.19
High density lipoprotein cholesterol (mg/dL)	48.51 ± 9.06	55.05 ± 7.14	48.66 ± 9.67

Data are presented as mean ± SD unless otherwise noted. Patients with non-alcoholic activity score (NAS) of five or higher were considered to have non-alcoholic steatohepatitis. Those with NAS equal to two or lower were defined as simple fatty liver[14]. NAFLD: Non-alcoholic fatty liver disease.