Endoscopy-based management decreases the risk of postoperative recurrences in Crohn’s disease

Table 1 Baseline characteristics of the 161 included Crohn’s disease patients at the time of surgery n (%)

Mean age at the time of surgery (yr)	36.4 ± 13.4	Adalimumab	22 (13.7)
Mean age at diagnosis (yr)	28.7 ± 13.1	Anti-TNF naive at the time of surgery	37 (23.0)
Median disease duration (yr) (IQR)	5.8 (2.0–11.7)	Type of surgery
Female gender	93 (57.8)	Ileocecal resection	76 (47.2)
Mean weight (kg)	60.2 ± 14.8	Ileal resection	21 (13.1)
Mean body mass index (kg/m²)	21.5 ± 4.9	Ileo-colectomy	14 (8.7)
Active smoker	53 (32.9)	Partial colectomy	31 (19.2)
Familial history of IBD	20 (12.4)	Subtotal colectomy	8 (5.0)
Previous appendectomy	67 (41.6)	Total colectomy	9 (5.6)
Previous intestinal resection	50 (31.1)	Abdomino-perianal amputation	2 (1.2)
Montreal classification		Site of anastomosis
Age at diagnosis		Ileo-colic	91 (66.4)
A1	15 (9.3)	Ileo-rectal	9 (6.6)
A2	116 (72.1)	Ileo-ileal	21 (15.3)
A3	28 (17.4)	Colo-colonic	31 (22.6)
Crohn’s disease location		Colo-rectal	7 (5.1)
L1	64 (39.8)	Stomia
L2	21 (13.0)	None	113 (70.2)
L3	75 (46.6)	Transitory	39 (24.2)
L4	18 (11.2)	Definitive	9 (5.6)
Crohn’s disease behaviour		Surgical technic of anastomosis
B1	12 (7.4)	Stapled	46 (43.8)
B2	75 (46.6)	Handsewn	59 (56.2)
B3	74 (46.0)	Type of anastomosis
Perianal lesions	69 (42.8)	Side-to-end	18 (18.0)
Anal ulceration, fissure	15 (9.3)	Side-to-side	54 (54.0)
Fistula/abscess	54 (33.5)	End-to-end	28 (28.0)
Medication at the time of surgery		Mean length of ileal resection (cm)	18.1 ± 17.1
5-ASA	24 (14.9)	Mean length of colonic resection (cm)	14.3 ± 17.7
Steroids	38 (23.6)	Mean length of digestive resection (cm)	31.6 ± 18.8
Budesonide	9 (5.6)	Perioperative complications	25 (16.8)
Thiopurines	36 (22.4)	Free margin resection	21 (17.1)
Methotrexate	5 (3.1)	Granuloma	47 (40.5)
Infliximab	15 (9.3)	Median CRP level, mg/L (IQR)	17.0 (3.8-61.0)

IQR: Interquartile; CRP: C-reactive protein; TNF: Tumor necrosis factor; IBD: Inflammatory bowel disease.