Immunological changes in different patient populations with chronic hepatitis C virus infection

doi:10.3748/wjg.v22.i20.4848

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May 28, 2016 (publication date) through Feb 7, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 28, 2016; 22(20): 4848-4859
Published online May 28, 2016. doi: 10.3748/wjg.v22.i20.4848

Table 1 Peripheral blood mononuclear cell phenotype characteristics in patients with chronic hepatitis C virus with elevated alanine aminotransferase or persistently normal alanine aminotransferase and in healthy individuals

	Healthy individuals	Chronic HCV with elevated ALT	HCV carriers with PNALT
Percentage of PBL
CD3+CD4+	29.38 ± 8.11	33.15 ± 9.08	34.46 ± 6.49
CD3+CD4+CD25+	4.27 ± 1.62	4.05 ± 1.57	5.24 ± 1.43
CD3+CD4+CD25^bright+	0.52 ± 0.26	0.38 ± 0.26	0.40 ± 0.13
CD3+CD56+	2.99 ± 1.73	5.07 ± 4.15	3.48 ± 2.72
CD3-CD56+	17.34 ± 7.42	16.42 ± 5.26	17.04 ± 7.71
CD3-CD56^dim+	16.04 ± 7.36	14.58 ± 5.72	15.92 ± 7.14
CD3-CD56^bright+	1.15 ± 0.64	1.75 ± 1.54	1.27 ± 1.01
CD3+CD8+	28.59 ± 4.55	25.27 ± 8.77	24.66 ± 6.14

Statistical comparisons were made by using the ANOVA tests. The results were expressed as the mean value ± SD. HCV: Hepatitis C virus; ALT: Alanine aminotransferase; PNALT: Persistently normal ALT; NK: Natural killer cell.

Citation: Szereday L, Meggyes M, Halasz M, Szekeres-Bartho J, Par A, Par G. Immunological changes in different patient populations with chronic hepatitis C virus infection. World J Gastroenterol 2016; 22(20): 4848-4859
URL: https://www.wjgnet.com/1007-9327/full/v22/i20/4848.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i20.4848