Targeted therapies in gastric cancer and future perspectives

doi:10.3748/wjg.v22.i2.471

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Jan 14, 2016 (publication date) through Nov 3, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 14, 2016; 22(2): 471-489
Published online Jan 14, 2016. doi: 10.3748/wjg.v22.i2.471

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Figure 1 Schematic view of targeted therapies in gastric cancer and sites of action. EGFR: Epidermal growth factor receptor; VEGFR: Vascular endothelial growth factor receptor; HGF: Hepatocyte growth factor; PI3K: Phosphatidylinositol 3-kinase; Akt: Protein kinase B; mTOR: Mammalian target of rapamycin; MAPK/MEK: Mitogen-activated protein kinases; Raf1: Serine/Threonine-Specific Protein Kinases; SOS: Small guanosine triphosphatases (GTPases); GRB2: Growth factor receptor-bound protein 2.

Citation: Yazici O, Sendur MAN, Ozdemir N, Aksoy S. Targeted therapies in gastric cancer and future perspectives. World J Gastroenterol 2016; 22(2): 471-489
URL: https://www.wjgnet.com/1007-9327/full/v22/i2/471.htm
DOI: https://dx.doi.org/10.3748/wjg.v22.i2.471