Chemokine/chemokine receptor pair CCL20/CCR6 in human colorectal malignancy: An overview

Table 2 CCL20 and CCR6 data in colorectal cancer available in the literature

Author	Year	Cell-lines	Clinical samples	Animal model	CCL20 determination	CCR6 determination	Functional assays	Ref.
Rossi	1997	Yes	No	No	SB, NB	No	No	[8]
Izadpanah	2001	Yes	Yes	No	IHC, PCR, ELISA	IHC, PCR	No	[27]
Fujiie	2001	Yes	No	No	ELISA, PCR	No	No	[28]
Kwon	2002	Yes	No	No	ELISA, PCR	No	No	[29]
Dellacasagrande	2003	No	Yes	Yes	No	PCR	AA	[43]
Yang	2005	Yes	No	No	No	FC, CM	cAMP, PP, CF	[32]
Brand	2006	Yes	Yes	No	PCR, IHC	PCR, IHC	PA, WA, APA	[33]
Ghadjar	2006	No	Yes	No	No	IHC	No	[34]
Rubie	2006	No	Yes	No	PCR, ELISA	PCR, WB	No	[35]
Liu	2011	Yes	No	Yes	IF, WB, PCR	FC, IF	No	[51]
Vicinus	2012	Yes	No	No	PCR, ELISA		miR, LUC	[42]
Hu	2013	No	Yes	No	No	IHC	No	[38]
Frick	2013	No	Yes	No	PCR, ELISA, IHC	PCR, IHC	No	[37]
Vicinus	2013	No	Yes	No	PCR, ELISA, IHC	No	No	[41]
Nandi	2014	Yes	Yes	Yes	ELISA, IHC	IHC, PCR, WB	No	[39]

SB: Southern blot; NB: Northern blot; PCR: Polymerase chain reaction; IHC: Immunohistochemistry; PA: Proliferation assay; ELISA: Enzyme-linked immunosorbent assay; AA: Actin assay; FC: Flow-cytometry; CM: Confocal microscopy; cAMP: cAMP assay; PP: Protein phosphorylation; CF: Calcium flux; WA: Wounding assay; APA: Apoptosis assay; WB: Western blot; IF: Immunofluorescece staining; miR: miRNA assay; LUC: Dual luciferase reporter assay.