Laparoscopic gastric cancer surgery: Current evidence and future perspectives

Table 1 Recent randomized clinical trials of laparoscopic vs open gastrectomy for the treatment of gastric cancer

Study	Year	Eligibility	Procedure	LND extent	No. of patient (LAG/OG)	Operative time	Blood loss	No. of retrieved LN	Hospital stay	Morbidity	Mortality
Kitano et al[1]	2002	cT1	LADG/ODG	Not mentioned	14/14	ODG	LADG	Equivalent	Equivalent	Equivalent	Equivalent
Fujii et al[15]	2003	cT1	LADG/ODG	Not mentioned	10/10	ODG	Equivalent	NE	NE	Equivalent	Equivalent
Hayashi et al[16]	2005	cT1	LADG/ODG	Not mentioned	14/14	ODG	Equivalent	Equivalent	LADG	NE	Equivalent
Huscher et al[17]	2005	cT1-4N0-2	TLDG/ODG	D1, D2	30/29	Equivalent	TLDG	Equivalent	TLDG	Equivalent	Equivalent
Lee et al[18]	2005	cT1	LADG/ODG	D2	24/23	ODG	Equivalent	Equivalent	Equivalent	LADG	NE
Kim et al[19]	2008	cT1N0-1	LADG/ODG	D1, D2	82/82	ODG	LADG	ODG	LADG	NE	NE
Kim et al[11]	2010	cT1-2N0-1	LADG/ODG	D1 + beta, D2	179/163	ODG	LADG	NE	NE	Equivalent	Equivalent
Cai et al[14]	2011	cT2-3	LAG/OG (DG, TG, PG)	D2	49/47	OG	Equivalent	Equivalent	Equivalent	Equivalent	NE
Sakuramoto et al[20]	2013	cT1	LADG/ODG	D1+beta	31/32	ODG	LADG	Equivalent	Equivalent	Equivalent	NE
Takiguchi et al[21]	2013	cTNMI	LADG/ODG	D1, D2	20/20	ODG	LADG	Equivalent	LADG	NE	NE
Aoyama et al[22]	2014	cTNMI	LADG/ODG	D1 + beta, D2	13/13	ODG	LADG	Equivalent	NE	Equivalent	Equivalent

LND: Lymph node dissection; LADG: Laparoscopy-assisted distal gastrectomy; TLDG: Totally laparoscopic distal gastrectomy; ODG: Open distal gastrectomy; LAG; Laparoscopy-assisted gastrectomy; OG: Open gastrectomy; DG: Distal gastrectomy; TG: Total gastrectomy; PG: Proximal gastrectomy; LN: Lymph node; NE: Not evaluated. Favored group in each value were shown.