Contrast-enhanced ultrasound of histologically proven hepatic epithelioid hemangioendothelioma

Table 3 Contrast enhanced ultrasound imaging features of hepatic epithelioid haemangioendothelioma and multilocular hemangioma/ focal nodular hyperplasia n (%)

Characteristic	HEHE(n = 25 patients)	Hemangioma/FNH(n = 45 patients)
Arterial phase
Rim like hyperenhancement	18 (72)	0
Heterogeneously hyperenhancement	7 (28)	6 (13.3)
Peripheral nodular enhancement	0	All hemangioma
Central arterial blood supply		All FNH
Portal-venous phase
Hyperenhancement	0	100 (100.0%)
Hypoenhancement	25 (100)	0
Isoenhancement	0	0
Late phase
Hyperenhancement	0	45 (100.0%)
Hypoenhancement	25 (100)	0
Isoenhancement	0	0
Sensitivity
Rim like hyperenhancement	18/25 (72)	0
Hypoenhancement at portal venous phase	25/25 (100)	0
Central unenhanced area at late phase
Yes	18 (72)	13 (28.9)
No	7 (28)	32 (71.1)

CEUS: Contrast enhanced ultrasound; HEHE: Hepatic epithelioid haemangioendothelioma; FNH: Focal nodular hyperplasia.