Correlation between Helicobacter pylori-associated gastric diseases and colorectal neoplasia

Table 4 Correlation between gastric intraepithelial neoplasia and colorectal neoplasia n (%)

Parameter	Total number of patients (n = 233)	Gastric intraepithelial neoplasia	Control group 1	OR	95%CI	P value
Age	56.85	57.68 ± 11.24	56.42 ± 14.90	-	-	-
Male	164	32 (19.5)	48 (29.3)	1.000	-	-
Female	69	5 (7.2)	36 (52.2)	0.208	0.074-0.588	0.002
Control group 2	95	9 (9.5)	40 (42.1)	1.000	-	-
Adenoma without HGIEN	92	21 (22.8)	30 (32.6)	3.111	1.248-7.753	0.013
Adenoma with HGIEN	16	1 (6.3)	3 (18.8)	1.481	0.138-15.941	1.000
Adenocarcinoma	27	5 (18.5)	11 (40.7)	2.020	0.561-7.272	0.306
Polyp number
1-3	106	17 (16.0)	36 (34.0)	2.099	0.832-5.293	0.112
4-9	46	10 (21.7)	14 (30.4)	3.175	1.071-9.413	0.033
10+	20	3 (15.0)	9 (45.0)	1.481	0.333-6.596	0.689
Adenoma size (mm)
0-9	82	16 (19.5)	25 (30.5)	2.844	1.092-7.410	0.029
10-19	30	4 (13.3)	9 (30.0)	1.975	0.496-7.868	0.444
20+	16	3 (18.8)	7 (43.8)	1.905	0.411-8.829	0.409
Polyp location
Rectum	79	12 (15.2)	33 (41.8)	1.616	0.607-4.304	0.335
Sigmoid colon	77	16 (20.8)	22 (28.6)	3.232	1.227-8.512	0.015
Descending colon	64	14 (21.9)	19 (29.7)	3.275	1.205-8.899	0.017
Transverse colon	55	13 (23.6)	17 (30.9)	3.399	1.223-9.443	0.016
Ascending colon	57	13 (22.8)	18 (31.6)	3.210	1.162-8.864	0.021

HGIEN: High-grade intraepithelial neoplasia.