Correlation between Helicobacter pylori-associated gastric diseases and colorectal neoplasia

Table 3 Correlation between gastric intestinal metaplasia and colorectal neoplasia n (%)

Parameter	Total number of patients (n = 233)	Gastric intestinal metaplasia	Control group 1	OR	95%CI	P value
Age	56.85	58.39 ± 7.34	56.42 ± 14.90	-	-	-
Male	164	44 (26.8)	48 (29.3)	1.000	-	-
Female	69	15 (21.7)	36 (52.2)	0.455	0.219-0.941	0.032
Control group 2	95	29 (30.5)	40 (42.1)	1.000	-	-
Adenoma without HGIEN	92	19 (20.7)	30 (32.6)	0.874	0.414-1.845	0.723
Adenoma with HGIEN	16	7 (43.8)	3 (18.8)	3.218	0.767-13.509	0.172
Adenocarcinoma	27	3 (11.1)	11 (40.7)	0.376	0.096-1.470	0.149
Polyp number
1-3	106	30 (28.3)	36 (34.0)	1.149	0.582-2.270	0.688
4-9	46	12 (26.1)	14 (30.4)	1.182	0.477-2.929	0.717
10+	20	5 (25.0)	9 (45.0)	0.766	0.232-2.527	0.661
Adenoma size (mm)
0-9	82	23 (28.0)	25 (30.5)	1.269	0.605-2.663	0.528
10-19	30	10 (33.3)	9 (30.0)	1.533	0.553-4.248	0.410
20+	16	1 (6.3)	7 (43.8)	0.197	0.023-1.690	0.140
Polyp location
Rectum	79	19 (24.1)	33 (41.8)	0.794	0.379-1.664	0.541
Sigmoid colon	77	24 (31.2)	22 (28.6)	1.505	0.710-3.187	0.285
Descending colon	64	17 (26.6)	19 (29.7)	1.234	0.549-2.775	0.611
Transverse colon	55	14 (25.5)	17 (30.9)	1.136	0.484-2.668	0.770
Ascending colon	57	12 (21.1)	18 (31.6)	0.920	0.384-2.201	0.851

HGIEN: High-grade intraepithelial neoplasia.