Correlation between Helicobacter pylori-associated gastric diseases and colorectal neoplasia

Table 2 Correlation between Helicobacter pylori-associated gastritis and colorectal neoplasia n (%)

Parameter	Total number of patients (n = 233)	H. pylori-associated gastritis	Control group 1	OR	95%CI	P value
Age	56.85	52.72 ± 11.37	56.42 ± 14.90	-	-	-
Male	164	27 (16.5)	48 (29.3)	1.000	-	-
Female	69	9 (13.0)	36 (52.2)	0.444	0.186-1.060	0.064
Control group 2	95	10 (10.5)	40 (42.1)	1.000	-	-
Adenoma without HGIEN	92	18 (19.6)	30 (32.6)	2.400	0.969-5.941	0.055
Adenoma with HGIEN	16	4 (25.0)	3 (18.8)	5.333	1.025-27.758	0.054
Adenocarcinoma	27	4 (14.8)	11 (40.7)	1.455	0.382-5.543	0.721
Polyp number
1-3	106	16 (15.1)	36 (34.0)	1.778	0.716-4.414	0.212
4-9	46	10 (21.7)	14 (30.4)	2.857	0.983-8.306	0.049
10+	20	3 (15.0)	9 (45.0)	1.333	0.304-5.852	0.703
Adenoma size (mm)
0-9	82	15 (18.3)	25 (30.5)	2.400	0.934-6.165	0.066
10-19	30	5 (16.7)	9 (30.0)	2.222	0.609-8.108	0.286
20+	16	4 (25.0)	7 (43.8)	2.286	0.558-9.366	0.256
Polyp location
Rectum	79	14 (17.7)	33 (41.8)	1.697	0.667-4.315	0.264
Sigmoid colon	77	12 (15.6)	22 (28.6)	2.182	0.813-5.856	0.118
Descending colon	64	13 (20.3)	19 (29.7)	2.737	1.018-7.357	0.043
Transverse colon	55	11 (20.0)	17 (30.9)	2.588	0.927-7.230	0.065
Ascending colon	57	11 (19.3)	18 (31.6)	2.444	0.880-6.787	0.082

HGIEN: High-grade intraepithelial neoplasia; H. pylori: Helicobacter pylori.